Greater New Haven has a strong foundation and several key elements that contribute to its status as a growing technology hub. The region's focus on biotechnology, startup support, collaboration, and access to talent makes it an attractive location for technology-driven entrepreneurs and companies. New Haven is a thriving technology hub with a supportive startup ecosystem. Yale University's expertise in computer science, biotech, and engineering has fostered innovation. Biotech companies and research centers have established a strong foundation for life sciences. Connecticut state initiatives and policies encourage tech sector growth and attract entrepreneurs and investors. The city benefits from a well-developed infrastructure and access to talented graduates from leading educational institutions.

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Yale University is the primary source for technology transfer in New Haven. Since 2000, over 60 startups based on Yale IP in the New Haven area have raised over $1.1 billion in venture capital and $11 billion from public markets. In 2019, the Yale Office of Cooperative Research and the Yale Entrepreneurial Institute reported 1,367 cumulative active patents in 60 countries.