The healthcare industry continues to thrive in Greater New Haven. Yale New Haven Health System is one of the largest health systems in the country and has expanded its footprint in Connecticut by acquiring additional hospitals and opening new ambulatory centers. Milford Hospital is now the Milford Campus of Bridgeport hospital which is YNHH facility. In addition, West Haven is home to the West Haven Campus of the VA Connecticut Healthcare System.

While the COVID-19 pandemic caused significant strain on the healthcare during the spring 2020 surge, the health system was able to implement critical improvements in based on research and practical experience. As of January 2021, the hospitals are performing elective surgeries while managing the needs of COVID-19 patients.